Higher resolution, better sensitivity, and excellent reproducibility: this is how Dynamic Image Analysis (DIA) improves the characterization of powders and granulates in both quality control and R&D. This white paper outlines how particle size distribution and particle shape are determined by DIA, illustrated by application examples from the pharmaceutical industry which prove the superiority of the method over sieve analysis and laser diffraction. Traditional techniques for particle size distribution analysis of pharmaceutical samples are sieve analysis, microscopy or laser diffraction. These methods are established in the pharmacopoeia and are used in pharmaceutical laboratories all over the world.